ATTENTION COVID-19. Global alert for the vaccinated… See more
The latest global alert and updates on COVID-19 vaccination as of September 2025 highlight several key points:
- The World Health Organization (WHO) has assessed the global public health risk from COVID-19 as moderate as of mid-2025, noting declining deaths and hospitalizations due to high population immunity and improved clinical management. However, COVID-19 continues to circulate widely with ongoing virus evolution and reduced vaccine uptake among high-risk groups, prompting WHO to recommend continued vaccination for high-risk individuals [3].
- In the US, a recent panel of advisers to the CDC discussed vaccine recommendations for the updated COVID-19 vaccine for the season. Modeling studies suggest that a universal vaccine recommendation for all ages could prevent substantially more hospitalizations and deaths compared to restricting recommendations to only high-risk groups. Despite this, the current trend in some advisory panels is to treat COVID-19 vaccination as a personal choice rather than a blanket recommendation [1][4][5][6].
- Pfizer reaffirmed the safety and efficacy of its COVID-19 vaccines in September 2025. They reported substantial effectiveness in preventing hospitalizations and severe illness, especially among older adults. The company also shared promising clinical trial data for the new 2025-2026 vaccine formula targeting adults 65+ and those with risk conditions [2][9].
- Amendments to the International Health Regulations entered into force on September 19, 2025, reflecting a global commitment to better cooperation in managing public health emergencies such as COVID-19 [8].
In summary, while the global COVID-19 risk has moderated, the virus remains a concern with ongoing vaccination recommended for vulnerable populations. There is debate in the US about broad vaccine mandates versus individual choice, but scientific data shows benefits of universal vaccination. Vaccine manufacturers continue to provide updated and effective vaccines to combat evolving variants.
Referencias:
[1] Recommending Covid-19 vaccines for everyone in the US … https://www.cnn.com/2025/09/18/health/covid-projections-vaccine-recommendations-study
[2] Pfizer Reaffirms Safety and Efficacy of COVID-19 Vaccines https://www.pfizer.com/news/announcements/pfizer-reaffirms-safety-and-efficacy-covid-19-vaccines
[3] COVID-19 Global Risk Assessment https://www.who.int/publications/m/item/covid-19-global-risk-assessment-v8
[4] CDC panel abandons COVID vaccine recommendation … https://abcnews.go.com/Health/cdc-hepatitis-bvaccine-vote-delayed-parents/story?id=125731004
[5] CDC vaccine advisers: Remove blanket recommendation … https://www.politico.com/news/2025/09/19/kennedys-vaccine-advisers-vote-to-remove-blanket-recommendation-that-older-americans-get-a-covid-19-vaccine-00573309
[6] RFK Jr. vaccine panel Covid shot recommendations https://www.cnbc.com/2025/09/19/rfk-jr-vaccine-panel-covid-shot-recommendations.html
[7] Quick takes: Moderate global COVID risk, California vaccine … https://www.cidrap.umn.edu/covid-19/quick-takes-moderate-global-covid-risk-california-vaccine-guidance-michigan-avian-flu
[8] Amended International Health Regulations enter into force https://www.who.int/news/item/19-09-2025-amended-international-health-regulations-enter-into-force
[9] Pfizer-BioNTech Statement to ACIP Meeting 19th … https://www.pfizer.com/news/announcements/pfizer-biontech-statement-acip-meeting-19th-september-2025
[10] Video CDC panel drops COVID-19 vaccine recommendations … https://abcnews.go.com/Health/video/cdc-panel-drops-covid-19-vaccine-recommendations-personal-125748681